Rhabdomyolysis due to the additive effect of statin therapy and hypothyroidism: a case report
نویسندگان
چکیده
We describe a patient with previously undiagnosed hypothyroidism who developed rhabdomyolysis while taking a statin. He had no other precipitating factors. The statin was stopped, intravenous fluids were started immediately and L-thyroxin was given after confirming the diagnosis of hypothyroidism. His symptoms improved over a few days. Because rhabdomyolysis is a rare but potentially life threatening disorder when complicated by acute tubular necrosis and renal failure, physicians must pay special attention when starting statins in patients with hyperlipidemia.
منابع مشابه
Rhabdomyolysis in the setting of induced hypothyroidism and statin therapy: a case report.
Mild elevation of creatine kinase (CK) is common in untreated hypothyroidism, but severe myositis and overt rhabdomyolysis are rare. Similarly, muscle pain and CK elevation are potential side effects of statin therapy, yet rhabdomyolysis is likewise rare in the absence of medication interactions adversely affecting statin metabolism. The coexistence of statin therapy and hypothyroid states may ...
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Rhabdomyolysis is a syndrome involving the breakdown of skeletal muscle that causes myoglobin and other intracellular proteins to leak into the circulatory system, resulting in organ injury including acute kidney injury. We report a case of statin-induced rhabdomyolysis and acute kidney injury that developed in a 63-year-old woman with previously undiagnosed hypothyroidism. Untreated hypothyroi...
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Statins are commonly used drugs in the treatment of hyperlipidemia (HL), despite some undesirable side effects. These range from mild symptoms such as myopathy, muscle weakness and myalgia to severe muscle weakness associated with chronic myopathy and acute renal failure (ARF) as a result of rhabdomyolysis. The most serious and deadly side effect of statins is rhabdomyolysis. The case presente...
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Background Rhabdomyolysis is considered a rare medical condition in pediatric population. Case Report We report our experience on a one year old girl referred to Shiraz Nemazee Hospital, Southern Iran with rhabdomyolysis due to severe hypernatremia, secondary to gastroenteritis. Discussion Rhabdomyolysis should be taken in to consideration in hypernatremic states, as it may lead to severe conse...
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عنوان ژورنال:
- Journal of Medical Case Reports
دوره 1 شماره
صفحات -
تاریخ انتشار 2007